Mission
The goal of the Bailey Laboratory is to make meaningful contributions to the fight against global infectious diseases through understanding the fundamental principles that govern viral transmission, immune evasion, and pathogenesis. This includes studying viruses in their “natural/reservoir” hosts in which they cause persistent sub-clinical infections, as well as in “non-natural” hosts that experience severe disease. We use in vitro and in vivo tools to understand how and why certain viruses preferentially infect specific cellular subsets (a.k.a. “tropism”), and how viral tropism intersects with the host immune response to shape the trajectory of disease. To advance our fundamental understanding of these complex processes, we have developed novel systems for studying several viruses that exhibit “extreme” behaviors within these themes (see diagram below). Providing a culture of curiosity, creativity, respect, and rigor in which the next generation of scientists can maximize their learning potential is also a critical component of the Bailey Lab’s mission.
